Medication For Autism and ADHD
Treatments for ADHD can help with symptoms of autism that are similar, such as hyperactivity and impulsivity. Medication can have side-effects.
Research is needed to better understand the effects of co-occurring symptoms on the outcomes of treatment. The stimulants methylphenidate (Ritalin) are usually used to treat ADHD. They can also aid in addressing autism-related symptoms that are overlapping.
Inattention Medications
Autism and attention deficit/hyperactivity disorder (ADHD) are two disorders that coexist. It is estimated that between 30 and 50% of those diagnosed with autism exhibit an elevated level of ADHD symptoms. This is relevant clinically and epidemiologically, because effective treatment of the primary symptoms of both disorders improves adaptive functioning and prevents negative coping behaviors [1 2, 3].
Inattention, impulsivity and hyperactivity are all signs of ADHD. The medications used to treat ADHD reduce these symptoms, and can improve social, academic and behavioral outcomes for individuals with co-occurring ADHD and autism.
In a longitudinal cohort study, researchers found that the percentage of individuals prescribed psychotropic drugs was similar for people with and without coexisting autism. However, the type of medication and frequency of prescriptions varied between the groups. The most frequently used medication was stimulant, followed by atomoxetine and SSRIs. In a subgroup study, people with ADHD-Combined as well as those with autism were more likely to receive ADHD medications, while children with ADHD-Inattentive had a lower chance to receive treatment than those with autism in isolation.
Stimulants increase the levels of norepinephrine, dopamine and other neurotransmitters that are found in your brain that are associated with motivation, reward, and decision-making. The use of stimulants has been proven to be effective in decreasing ADHD symptoms among children with autism and ADHD. However certain patients may experience adverse reactions such as stomach problems, headaches and insomnia.
Nonstimulant medications, such as atomoxetine or guanfacine also seem to decrease ADHD symptoms in people with autism and ADHD. Indirect, low-quality research suggests the atypical antipsychotics, such as aripiprazole or risperidone could reduce irritability among children suffering from ASD. However, further studies are needed to determine whether this is due to a reduction in ADHD symptoms or a change in the core ASD behaviors.
Enhanced understanding of co-occurring symptom patterns can assist clinicians to optimize the duration and timing of psychosocial versus pharmacological treatment for each disorder, and also to determine the critical times when interventions may be more efficient. More suggestions of co-occurring symptom patterns and how they interact with time will aid in identifying optimal treatment interventions to mitigate the negative effects of ADHD symptoms on ASD essential functions.
Treatments for Hyperactivity

Although few research studies have compared psychopharmacological treatment for coexisting ADHD and autism, available data suggests that individuals with both conditions may benefit from optimal use of medication. A number of clinical trials suggest that stimulant medications (methylphenidate and atomoxetine) enhance core ADHD symptoms for children and adolescents with ASD.
The same drugs have been shown to boost social skills in people with autism. These medications are not risk-free and should only ever be administered by a physician who is knowledgeable about the risks and benefits of each medication. Additionally, individuals with autism may react differently to different medications, and certain medications can be hazardous in certain situations.
A large-scale study on the population discovered that two thirds of children ages 6 to 11 and three quarters of adolescents between the ages of 12 and 17 with co-occurring ADHD and autism were taking some kind of psychotropic medication. This was in line with the prevalence of psychiatric drug usage among children and teens with ADHD on their own. Comorbid diagnoses of intellectual disability, schizophrenia, OCD, and substance abuse disorders were more frequent in people with ADHD and ASD than those with ADHD alone.
This study also found that individuals with coexisting ADHD and ASD were less likely to start and continue continuous psychopharmacological treatment than those with ADHD alone. This is due to the higher rates of discontinuation among ASD patients due to adverse effects such as irritability and difficulty in absorbing methylphenidate doses.
Comorbid ADHD and Autism are associated with more severe impairments than each condition alone. Therefore it is essential to improve the treatment of both disorders. Research should focus on finding the most effective psychosocial therapies for co-occurring ADHD and autism. These include the use of behavioral therapies, parent education as well as social skills therapy. These therapies are known to decrease disruptive behavior that are associated with ADHD and autism. Future research should also investigate the developmental trajectories for co-occurring disorders to determine whether symptoms change during course development and how that influences the treatment. This research will allow us to create more specific interventions that are tailored to the needs of people with ADHD and ASD.
Medications for Anxiety
Autism is a complex and difficult disorder that can trigger problems in many areas, including emotions, sleep, concentration and behavior. While non-medical treatment is usually the first option, medication can often provide relief and provide parents and children tools to aid them in achieving their goals. The use of medications to treat ADHD can also offer a significant boost in the ability to manage some of the depression and anxiety that are prevalent among those with autism.
Stimulant medication can be helpful in treating the "core" ADHD symptoms which interfere with academic, social and behavioral development. For example, improving the ability to focus and complete tasks can make a an enormous difference in reading, writing, and other academic abilities. Medications can bring noticeable improvement in the ability to interact with others and also reduce the frequency of self-injurious behavior, tantrums and aggression may decrease too.
Antidepressants may be prescribed to children with autism to decrease their irritability and improve their mood. These medicines include fluoxetine and are known as selective serotonin reuptake inhibitors (SSRIs). SSRIs have been proven to reduce depression, anxiety, and other conditions for those with autism, but larger clinical trials are needed to confirm these effects.
medication for adhd , such as risperidone and Aripiprazole are utilized to control the irritability and emotional outbursts that are common to people with autism. FDA has not approved these drugs to treat autism. However, they could be useful in improving the control of emotions in both adults and children.
Researchers are also examining how co-occurring ADHD and autism impact symptom trajectory over time. A better understanding of these connections will hopefully enable more targeted pharmacological and psychosocial treatments.
It is important to understand that medication can cause negative side effects and must be handled with caution. It is also a good idea to explore alternatives before beginning treatment with medication, particularly for young children. However, when properly titrated, these drugs can be an effective tool to improve the quality of life of those suffering from autism and ADHD.
Treatments for Emotions
When a child with autism suffers from overwhelming anxiety or depression the symptoms can become so severe they interfere with their daily functioning. In these cases doctors may prescribe medications to manage their emotions.
Medications for ADHD can also be used to lessen anxiety and impulsivity, which are common in autism. These medications are usually used in conjunction with other behavioral treatments. A variety of medications, including SSRIs can help alleviate anxiety and depression in people with autism. Other medications, like antipsychotics with atypical properties and alpha-2 antagonists, can help reduce irritability among people with autism.
Researchers have recognized that autism and ADHD are often seen together despite being distinct diagnoses. It is estimated that about half of children who are diagnosed with autism display ADHD symptoms, such as inattention and hyperactivity. This is why many families find that they have to take medications to treat both disorders.
Adults and children suffering from ADHD and autism are typically treated by medication. It is not intended to cure autism, or to eliminate all related behaviors. Instead, it can help manage specific symptoms that make it difficult to function in school and socially.
Research shows that atypical antipsychotics like risperidone can reduce irritability and aggression in some people with autism. These medications can also ease the psychotic symptoms, such as hallucinations or delusions that may be present in those with autism.
It is crucial to understand that the majority of medications approved by Health Canada were not studied specifically on children or youths with autism. The majority of them have followed a standard method to be put on the market, which includes the observation of a small group of people with positive results, publishing of case studies, more off-label use, open-label trials, and finally placebo-controlled controlled randomized study.
The most frequently prescribed medications for adolescents and adults with co-occurring ASD and ADHD are methylphenidate (Ritalin, Concerta, Metadate), amphetamines (Adderall, Dexedrine, Vyvanse) and the atomoxetine (Strattera). These are also frequently prescribed for children suffering from pure ADHD. Medications to treat anxiety, such as SSRIs, benzodiazepines and other anti-seizure medications, haven't been thoroughly researched in this population, so the evidence for their effectiveness is less compelling.